MycoBiomDB – Record Details (MyCo_6239)

Biomarker Record Details

Database ID: MyCo_6239
DB IDMyCo_6239
TitleProteomic demonstration of the recurrent presence of inter-alpha-inhibitor H4 heavy-chain during aspergillosis induced in an animal model
Year2013
PMID24360996
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThis protocol was based on the animal model approved by the ethics committee for animal experimenta-tion of Val-de-Loire (France).
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupAnimal
Host Common nameRat
Host Scientific nameRattus norvegicus
Biomarker NameITIH4
Biomarker Full NameInter-alpha-inhibitor H4 heavy-chain
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
Cohort7 six- to eight-week-old male Sprague-Dawley rats (Janvier®) were immunocompro- mised by repeated intraperitoneal injections of cyclophosphamide (Endoxan® BaxterTM).
Cohort No.None
Age GroupNone
P Valuep<0.01
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueBioinformatics analysis
Analysis MethodProteomics Approach
ELISA kitsNone
Assay DataNone
Validation Techniques usedProteomics Approach
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone