| DB ID | MyCo_6234 |
| Title | Proteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans |
| Year | 2020 |
| PMID | 33043780 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The study, involving the collection of BAL samples and patient metadata, was approved by the Ethics Subcommittee for Life and Health Sciences (SECVS), University of Minho, Portugal (no. 126/2014), and the Ethics Committee of the University Hospitals of Leuven, Belgium. All animal experiments were carried out in accordance with the German animal protection law and were approved by the responsible Federal State authority’s (Thüringer Landesamt für Lebensmittelsicherheit und Verbraucherschutz) Ethics Committee (permit no. 03-014/15). |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | Hybrid NRPS/PKS enzyme, putative |
| Biomarker Full Name | Hybrid NRPS/PKS enzyme, putative |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Germany |
| Cohort | IPA patients (n = 27) non- IPA patients (n = 27) |
| Cohort No. | 27 Patients and 27 control |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Bioinformatics analysis |
| Analysis Method | Proteomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Proteomics Approach |
| Up Regulation Down Regulation | Positive |
| Sequence Data | Protein ID: B0YAW2 |
| External Link | None |
