MycoBiomDB – Record Details (MyCo_6057)

Biomarker Record Details

Database ID: MyCo_6057
DB IDMyCo_6057
TitleDecoding serological response to Candida cell wall immunome into novel diagnostic, prognostic, and therapeutic candidates for systemic candidiasis by proteomic and bioinformatic analyses
Year2005
PMID16195222
Fungal Diseases involvedSystemic candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker Nameanti-Bgl2p
Biomarker Full Nameanti-1,3-β-glucosidase
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortBetween December 1997 and March 2003, serum specimens from 48 patients with lab- oratory-confirmed SC belonging to different risk groups were ob- tained on the day of culture sampling at the Salamanca University Hospital (Spain) after informed consent was given. To provide data on assay specificity, serum samples from 118 individuals without clinical or microbiologi- cal evidence of SC and with a similar age and sex distribution to cases were evaluated as controls.
Cohort No.48 Patients and 118 control
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueBioinformatics analysis
Analysis MethodProteomic based Bioinformatic Analyses
ELISA kitsNone
Assay DataNone
Validation Techniques usedProteomic based Bioinformatic Analyses
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone