| DB ID | MyCo_6049 |
| Title | Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection |
| Year | 2019 |
| PMID | 31428097 |
| Fungal Diseases involved | Pulmonary Mold infection |
| Associated Medical Condition | None |
| Genus | None |
| Species | None |
| Organism | None |
| Ethical Statement | The study protocol was approved by the local ethics committee, Medical University Graz, Austria (EC-numbers 25-221 and 23-343), and registered at ClinicalTrials.gov (Identifier: NCT02058316 and NCT01576653). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-8 |
| Biomarker Full Name | Interleukin-8 |
| Biomarker Type | Prognostic |
| Biomolecule | Protein |
| Geographical Location | Austria |
| Cohort | Participants undergoing bronchoscopy were prospectively enrolled at the Medical University of Graz, Graz, Austria, between April 2014 and July 2017. This cohort study included 106 prospectively enrolled adult cases undergoing bronchoscopy. Blood samples were collected within 24 h of BAL sampling and, in a subset of 62 patients, serial blood samples were collected up until 4 days after bronchoscopy. |
| Cohort No. | 62 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | ProcartaPlex R ⃝ immunoassay |
| ELISA kits | (Platelia enzyme immunoassay; Bio-Rad Laboratories, Vienna, Austria) |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | ProcartaPlex R ⃝ immunoassay, GM-Platelia™ Aspergillus Ag ELISA, FDA approved Fungitell assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
