| DB ID | MyCo_6046 |
| Title | C-reactive protein and procalcitonin to discriminate between tuberculosis, Pneumocystis jirovecii pneumonia, and bacterial pneumonia in HIV-infected inpatients meeting WHO criteria for seriously ill: a prospective cohort study |
| Year | 2018 |
| PMID | 30107791 |
| Fungal Diseases involved | Pneumocystis jirovecii pneumonia |
| Associated Medical Condition | None |
| Genus | Pneumocystis |
| Species | jirovecii |
| Organism | Pneumocystis jirovecii |
| Ethical Statement | The University of Cape Town’s Human Research Ethics Committee approved the study protocol (reference 334/2011). All enrolled participants signed informed consent. Confused participants were enrolled and given the option to continue with participation once they were orientated. If they declined to give consent their data was removed. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Sputum sample |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Procalcitonin |
| Biomarker Full Name | Procalcitonin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | South Africa |
| Cohort | Two hundred forty-eight participants met study case definitions: 133 with tuberculosis, 61 with CAP, 16 with PJP, and 38 with mixed infection. |
| Cohort No. | 248 |
| Age Group | 28.9–40.7 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Assay |
| Analysis Method | Procalcitonin Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | CRP Assay, Procalcitonin Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
