MycoBiomDB – Record Details (MyCo_5936)

Biomarker Record Details

Database ID: MyCo_5936
DB IDMyCo_5936
TitleIntroducing biomarkers for invasive fungal disease in haemato-oncology patients: a single-centre experience
Year2022
PMID35819894
Fungal Diseases involvedInvasive fungal infection
Associated Medical ConditionNeutropaenic haemato-oncology patients
GenusNone
SpeciesNone
OrganismNone
Ethical StatementEthical approval was obtained from the Cambridge University Hospitals NHS Foundation Trust (UK) Audit Committee.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUK
CohortCambridge University Hospitals NHS Foundation Trust is a British Committee for Standards in Haematology level 3 referral hospital offering outpatient and inpatient haemato-oncology services, including haematopoietic stem cell transplantation. In total, 302 patients were identified prior to the institution of the pathway and 308 patients after introduction of the pathway. The two cohorts were well matched in terms of sex, age, haematological diagnosis and transplant status.
Cohort No.610
Age Group15-89
P Valuep=0.001
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodSerum Aspergillus PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedSerum Aspergillus PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone