MycoBiomDB – Record Details (MyCo_5921)

Biomarker Record Details

Database ID: MyCo_5921
DB IDMyCo_5921
TitleLymphocyte apoptosis in murine Pneumocystis pneumonia
Year2009
PMID19558669
Fungal Diseases involvedPneumocystis pneumonia
Associated Medical ConditionNone
GenusPneumocystis
Speciesmurina
OrganismPneumocystis murina
Ethical StatementNone
Site of InfectionLungs
Opportunistic invasiveOpportunistic
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameBim
Biomarker Full NameBim
Biomarker TypeDiagnostic
BiomoleculemRNA
Geographical LocationUSA
CohortSpecific pathogen-free BALB/c mice were purchased at 8 weeks of age from NCI/Charles River Breeding Labs (Wilmington, MA). Animals were housed in filter-topped cages and fed autoclaved chow and water ad libitum. Ani- mals were injected intratracheally with Pneumocystis at a dose of 2 × 105 cysts per mouse.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedRT-PCR, Flow cytometry
Up Regulation Down RegulationIncrease
Sequence DataGeneBank accession no. AF032459
External LinkNone