MycoBiomDB – Record Details (MyCo_5911)

Biomarker Record Details

Database ID: MyCo_5911
DB IDMyCo_5911
TitleInflammatory Ly6Chigh Monocytes Protect against Candidiasis through IL-15-Driven NK Cell/Neutrophil Activation
Year2017
PMID28636955
Fungal Diseases involvedCandidemia
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementAll the experiments were approved by the Animal Care and Use Committee of the Centro Nacional de Biotecnologı ´a-CSIC, Madrid, under the protocol number 312.14
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtraxted Kidney tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameIL-
Biomarker Full NameInterleukin-15
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortC57BL/6 mice were purchased from Charles River (L’Arbresle, France). Ccr2 / mice were kindly supplied by Dr. F. Tacke (RWTH- University Hospital Aachen, Aachen, Germany). Ifnar1 / mice were kindly provided by Dr. U. Kalinke (Center for Experimental and Clinical Infection Research, Hannover, Germany). Il15 / mice were kindly supplied by Dr. J. di Santo (Institut Pasteur, Paris, France).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis, RT-PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone