| DB ID | MyCo_5785 |
| Title | Myeloid-derived suppressor cells impair alveolar macrophages through PD-1 receptor ligation during Pneumocystis pneumonia |
| Year | 2014 |
| PMID | 25404033 |
| Fungal Diseases involved | Pneumocystis pneumonia |
| Associated Medical Condition | None |
| Genus | Pneumocystis |
| Species | spp. |
| Organism | Pneumocystis spp. |
| Ethical Statement | The study was approved by the Indiana University Animal Care and Use Committee and carried out under the supervision of veterinarians. |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | PD-L1 |
| Biomarker Full Name | PD-L1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | C57BL/6 mice were obtained from Harlan (India- napolis, IN). All animals used in this study were female, 18 to 20 g in weight. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | qRT-PCR, Western blot analysis, Flow cytometry, ChIP analysis |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
