| DB ID | MyCo_5764 |
| Title | Polymorphism analysis of the CTLA-4 gene in paracoccidioidomycosis patients |
| Year | 2011 |
| PMID | 21537684 |
| Fungal Diseases involved | Paracoccidioidomycosis |
| Associated Medical Condition | None |
| Genus | Paracoccidioides |
| Species | spp. |
| Organism | Paracoccidioides spp. |
| Ethical Statement | This study was approved by the ethical committee of the Brasília University and informed consent was obtained from each subject or their parent or guardian before sampling. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CTLA-4 |
| Biomarker Full Name | CTLA-4 |
| Biomarker Type | Negative |
| Biomolecule | Gene |
| Geographical Location | Brazil |
| Cohort | Samples from 66 PCM pa- tients diagnosed with the chronic form (aged 13-70, non- related males and females) comprised the test group and were collected from the southeastern and central-west Brazilian regions, both considered endemic areas. The control group was made up of 76 volunteers (aged 9-75, non-related males and females) from the central-west re- gion, none of whom had ever contracted PCM. |
| Cohort No. | 66 Patients and 76 control |
| Age Group | Sep-75 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | qRT-PCR |
| Up Regulation Down Regulation | Negative |
| Sequence Data | None |
| External Link | None |
