MycoBiomDB – Record Details (MyCo_5718)

Biomarker Record Details

Database ID: MyCo_5718
DB IDMyCo_5718
TitleHapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans
Year2010
PMID21124817
Fungal Diseases involvedCryptococcus neoformans infection
Associated Medical ConditionNone
GenusCryptococcus
Speciesneoformans
OrganismCryptococcus neoformans
Ethical StatementThis study was carried out in strict accordance with the guidelines of the Canadian Council on Animal Care. The protocol for the virulence assays employing mice (protocol A08-0586) was approved by the University of British Columbia Committee on Animal Care.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameHapX
Biomarker Full NameHapX
Biomarker TypeNegative
BiomoleculeProtein
Geographical LocationCanada
CohortThe virulence of each cryptococcal strain was examined using female BALB/c mice (4 to 6 weeks old) from Charles River Laboratories (Ontario, Canada).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodqRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedqRT-PCR
Up Regulation Down RegulationNegative
Sequence DataNone
External LinkNone