| DB ID | MyCo_5718 |
| Title | HapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans |
| Year | 2010 |
| PMID | 21124817 |
| Fungal Diseases involved | Cryptococcus neoformans infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | This study was carried out in strict accordance with the guidelines of the Canadian Council on Animal Care. The protocol for the virulence assays employing mice (protocol A08-0586) was approved by the University of British Columbia Committee on Animal Care. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | HapX |
| Biomarker Full Name | HapX |
| Biomarker Type | Negative |
| Biomolecule | Protein |
| Geographical Location | Canada |
| Cohort | The virulence of each cryptococcal strain was examined using female BALB/c mice (4 to 6 weeks old) from Charles River Laboratories (Ontario, Canada). |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | qRT-PCR |
| Up Regulation Down Regulation | Negative |
| Sequence Data | None |
| External Link | None |