| DB ID | MyCo_5714 |
| Title | Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection |
| Year | 2010 |
| PMID | 21224057 |
| Fungal Diseases involved | Cryptococcal Lung infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | The study protocol was approved by the local Department of Veterans Affairs Institutional Animal Care and Use Committee. |
| Site of Infection | Lungs |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Lungs tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | CCR2 |
| Biomarker Full Name | Chemokine Receptor 2 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Specific pathogen-free, inbred, female, wild-type BALB/c mice (designated CCR2 / in experiments involving direct comparison with CCR2 / mice), purchased from Charles River Laboratory Inc, Wilmington, MA, were used, except as specified. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis, qRT-PCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |