MycoBiomDB – Record Details (MyCo_5714)

Biomarker Record Details

Database ID: MyCo_5714
DB IDMyCo_5714
TitleChemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection
Year2010
PMID21224057
Fungal Diseases involvedCryptococcal Lung infection
Associated Medical ConditionNone
GenusCryptococcus
Speciesneoformans
OrganismCryptococcus neoformans
Ethical StatementThe study protocol was approved by the local Department of Veterans Affairs Institutional Animal Care and Use Committee.
Site of InfectionLungs
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted Lungs tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameCCR2
Biomarker Full NameChemokine Receptor 2
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortSpecific pathogen-free, inbred, female, wild-type BALB/c mice (designated CCR2 / in experiments involving direct comparison with CCR2 / mice), purchased from Charles River Laboratory Inc, Wilmington, MA, were used, except as specified.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodqRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis, qRT-PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone