MycoBiomDB – Record Details (MyCo_5704)

Biomarker Record Details

Database ID: MyCo_5704
DB IDMyCo_5704
TitleCytokine mRNA in brain tissue from mice that show strain-dependent differences in the severity of lesions induced by systemic infection with Candida albicans yeast
Year1995
PMID7658077
Fungal Diseases involvedCandida albicans infection
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameTNF-α
Biomarker Full NameTumor Necrosis Factor alpha
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationNedlands
CohortBALB/c and CBA/CaH mice were purchased from the Animal Resources Centre (Perth, Australia). The animals were bred under specific pathogen - free conditions and did not carry C. albicans in the gut.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodqRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedqRT-PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone