| DB ID | MyCo_5703 |
| Title | The GITRL-GITR system alters TLR-4 expression on DC during fungal infection |
| Year | 2009 |
| PMID | 19272591 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | Protocols were approved by the Animal Study Committees of the University of Perugia according to governmen-tal guidelines for animal care. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | TLR-4 |
| Biomarker Full Name | Tool like receptor-4 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Italy |
| Cohort | Sv129 GITR-deficient (GITR / ) mice were generated by homol-ogous recombination. Mice were maintained under specific-pathogen-free conditions in the Animal Care Facility of the University of Perugia. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | ELISA kits (BD Biosciences Pharmingen). |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis, qRT-PCR, ELISA, Western blotting |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
