MycoBiomDB – Record Details (MyCo_5622)

Biomarker Record Details

Database ID: MyCo_5622
DB IDMyCo_5622
TitleThe Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection
Year2020
PMID32084267
Fungal Diseases involvedFungal keratitis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementPatients consented to the management of samples, and the experiment was approved by the Institutional Research Ethics Committee at the Affiliated Hospital of Qingdao University.
Site of InfectionEye
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceCorneal samples
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameIL-10
Biomarker Full NameInterleukin-10
Biomarker TypeDiagnostic
BiomoleculeGene
Geographical LocationChina
CohortA total of 20 cornea samples of patients with FK (Fusarium 9,Aspergillusinfection 11; aged 40–70 years) and remaining tissues of 20 healthy donors used for keratoplasty were collected as control groups.
Cohort No.20
Age Group40-70
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniquePCR
Analysis MethodqRT-PCR
ELISA kitsNone
Assay DataNone
Validation Techniques usedWestern Blot Analysis, qRT-PCR
Up Regulation Down RegulationUp regulated
Sequence DataGenBank No. NM_010548.2
External LinkNone