| DB ID | MyCo_5618 |
| Title | The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection |
| Year | 2020 |
| PMID | 32084267 |
| Fungal Diseases involved | Fungal keratitis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | Patients consented to the management of samples, and the experiment was approved by the Institutional Research Ethics Committee at the Affiliated Hospital of Qingdao University. |
| Site of Infection | Eye |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Corneal samples |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | HMGB1 |
| Biomarker Full Name | HMGB1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | China |
| Cohort | Specificpathogen-freeC57BL/6mice(female,8weeks)were purchased from Changzhou Cavens Laboratory Animal Co., Ltd. (Jiangsu, China). The animals were treated according to the Statement for the Use of Animals in Ophthalmic and Vision Research made by the ARVO. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Western Blot Analysis, qRT-PCR |
| Up Regulation Down Regulation | Up regulated |
| Sequence Data | GenBank No. NM-000071.6 |
| External Link | None |
