| DB ID | MyCo_5601 |
| Title | Prospective multicentre PCR-based Aspergillus DNA screening in high-risk patients with and without primary antifungal mould prophylaxis |
| Year | 2016 |
| PMID | 26400571 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | Haematopoietic stem cell transplantation or chemotherapy for acute leukaemia |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | The study was approved by the local ethics committees of the MUI (Ethikommission der Medizinischen Universität Innsbruck, UN4529). UKW and HEL tested their samples as part of routine diagnostic care. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | ITS |
| Biomarker Full Name | Internal Transcribed Spacer |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | Austria |
| Cohort | Over a period of 2 years, twice-weekly serum samples were taken from allogeneic haematopoietic stem cell transplant re- cipients and patients receiving myelosuppressive chemotherapy during hospitalization and admitted to the Department for In- ternal Medicine II, University Hospital Würzburg (UKW), Germany, Internal Medicine V, University Hospital Innsbruck, and Internal Medicine, Hospital Elisabethinen, Linz (HEL), Austria. wo thousand one hundred and twenty-eight sera from 213 patients were investigated and strati ed according to the revised European Organization for the Research and Treatment of Cancer/Mycoses Study Group criteria for invasive fungal disease. |
| Cohort No. | 213 |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.714 |
| Specificity | 0.923 |
| Positive Predictive Value | 0.625 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | qRT-PCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
