| DB ID | MyCo_5588 |
| Title | Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation |
| Year | 2014 |
| PMID | 24848632 |
| Fungal Diseases involved | Mucormycosis |
| Associated Medical Condition | allogeneic bone marrow transplantation |
| Genus | Rhizomucor |
| Species | pusillus |
| Organism | Rhizomucor pusillus |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Rhizomucor DNA |
| Biomarker Full Name | DNA |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | A 3-year-old boy with a history of recurrent perianal abscess since the age of 6 months was admitted to our hospital to receive HSCT. At the age of 2 years, he had suffered from severe pneumonia of unknown etiology was included in the study. |
| Cohort No. | 1 |
| Age Group | 3 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Mucormycosis is a rapid, aggressive, and angioinvasive infection caused by fungi of the order Mucorales. A meta-analysis showed that 96 % of patients with dissemi- nated disease had died. The high mortality may be due to the lack of serum biomarkers useful for early diagnosis and prediction of disease progression. |
| Technique | PCR |
| Analysis Method | qPCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | qPCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
