| DB ID | MyCo_5521 |
| Title | An improved molecular diagnostic assay for canine and feline dermatophytosis |
| Year | 2013 |
| PMID | 22686247 |
| Fungal Diseases involved | Dermatophytosis |
| Associated Medical Condition | None |
| Genus | Microsporum |
| Species | canis |
| Organism | Microsporum canis |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Hair |
| Sample source | Hair |
| Host Group | Animal |
| Host Common name | Dog |
| Host Scientific name | Canis lupus familiaris |
| Biomarker Name | Chs-1 |
| Biomarker Full Name | Chitin synthase 1 gene |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | Italy |
| Cohort | From March 2009 to March 2010, 183 animals (87 dogs and 96 cats) suspected of having dermatophytic infections were examined clinically in the Faculty of Veterinary Medicine of Bari, Italy. In addition, this study included healthy domestic animals, i.e., 14 dogs and 36 cats without skin lesions, cohabiting with owners diagnosed with tinea corporis caused by M. canis . |
| Cohort No. | 183 |
| Age Group | None |
| P Value | None |
| Sensitivity | 1 |
| Specificity | 94.10% |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Dermatophytoses are superfi cial, cutaneous mycoses caused by dermatophytes, which are fi lamentous fungi that invade keratinized tissues (i.e., skin, hair and/or nails) of animals, including humans Dermatophytes are usually categorized into anthropo- philic, zoophilic or geophilic species, according to their habitat. Zoophilic dermatophytes infect both animals and humans, whereas anthropophilic dermatophytes selec- tively infect humans, often leading to mild to severe, local- ized and/or diffuse skin disease. |
| Technique | PCR |
| Analysis Method | PCR Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | PCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
