| DB ID | MyCo_5478 |
| Title | The ceja-1 sequence as a potential new molecular marker for Paracoccidioides brasiliensis infection |
| Year | 2010 |
| PMID | 19389074 |
| Fungal Diseases involved | Paracoccidioidomycosis |
| Associated Medical Condition | None |
| Genus | Paracoccidioides |
| Species | brasiliensis |
| Organism | Paracoccidioides brasiliensis |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Biopsy |
| Sample source | Extracted DNA |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Ceja-1 |
| Biomarker Full Name | Ceja-1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | UK |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Paracoccidioidomycosis (PCM), a systemic mycosis caused by the fungus Paracoccidioides brasiliensis, is highly prevalent in Latin American countries. It has been estimated that 10 million individuals are infected with it. The mycosis primarily affects the lungs but may subsequently spread to other organs or systems. The severity of the disease depends on the host immune response and the fungal virulence. An early diagnosis and treatment may avoid the development of severe acute form and the chronic clinical form. |
| Technique | PCR |
| Analysis Method | Heminested PCR (HN-PCR) |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Heminested PCR (HN-PCR), Electrophoresis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
