| DB ID | MyCo_5378 |
| Title | Immune-Response Patterns and Next Generation Sequencing Diagnostics for the Detection of Mycoses in Patients with Septic Shock-Results of a Combined Clinical and Experimental Investigation |
| Year | 2017 |
| PMID | 28820494 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | Septic Shock |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The observational clinical study was approved by the local ethics committee (Ethics Committee of the Medical Faculty of Heidelberg, Trial Code No. S-097/2013/German Clinical Trials Register: DRKS00005463) and was conducted in the surgical intensive care unit of Heidelberg University Hospital, Germany, between November 2013 and January 2015. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Plasma |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | ADM |
| Biomarker Full Name | Adrenomedullin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Germany |
| Cohort | In total 50 patients suffering from septic shock according to the criteria of the Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012 were enrolled in this study |
| Cohort No. | 50 |
| Age Group | 61-75 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Bioinformatics analysis |
| Analysis Method | Next Generation Sequencing Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis, Next Generation Sequencing Approach |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
