MycoBiomDB – Record Details (MyCo_5368)

Biomarker Record Details

Database ID: MyCo_5368
DB IDMyCo_5368
TitleIncreasing Total Serum IgE, Allergic Bronchopulmonary Aspergillosis, and Lung Function in Cystic Fibrosis
Year2017
PMID28526275
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionCystic fibrosis
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementThe study was approved by the local research ethics board (EK 16/5/2008).
Site of InfectionLungs
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTotal Serum IgE
Biomarker Full NameTotal Serum Immunoglobulin E
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortThe study included patients of all age seen at least once in the CF outpatient service from January 1, 2000, to December 31, 2006. A total of 387 children and young adults were followed from 2000 to 2006 and retrospectively classified into 6 groups.
Cohort No.387
Age Group0-41.6
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodN Latex IgE mono analysis
ELISA kitsNone
Assay DataN Latex IgE mono assay , BN ProsSpec System, Siemens AG, Munich, Germany
Validation Techniques usedN Latex IgE mono analysis
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone