MycoBiomDB – Record Details (MyCo_5305)

Biomarker Record Details

Database ID: MyCo_5305
DB IDMyCo_5305
TitleTwo dimensional difference gel electrophoresis analysis of cerebrospinal fluid in tuberculous meningitis patients
Year2011
PMID21723968
Fungal Diseases involvedCryptococcal meningitis
Associated Medical ConditionNone
GenusCryptococcus
Speciesspp.
OrganismCryptococcus spp.
Ethical StatementThe study was approved by ethics committee of the institute (IEC approval no. B-07: 02/05/2005).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceCerebrospinal fluid (CSF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameArachidonate 5-lipoxygenase
Biomarker Full NameArachidonate 5-lipoxygenase
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationIndia
CohortAll 8 patients with fungal meningitis were diagnosed with cryptococcal meningitis and were screened for India ink stain test, fungal culture and latex agglutination test
Cohort No.8
Age Group39.08 ± 5.54
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueElectrophoresis
Analysis MethodMS based 2-dimensional difference gel electrophoresis (2D-DIGE)
ELISA kitsNone
Assay DataNone
Validation Techniques usedMS based 2-dimensional difference gel electrophoresis (2D-DIGE), Western blot analyses
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone