| DB ID | MyCo_5303 |
| Title | Characterization of BBB permeability in a preclinical model of cryptococcal meningoencephalitis using magnetic resonance imaging |
| Year | 2008 |
| PMID | 19066614 |
| Fungal Diseases involved | Cryptococcus neoformans meningoencephalitis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | The study was approved by the University of New Mexico Institutional Animal Use committee and conformed to the National Institutes of Health guidelines for the ethical use of animals. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | None |
| Sample source | None |
| Host Group | Animal |
| Host Common name | Rat |
| Host Scientific name | Rattus norvegicus |
| Biomarker Name | T2w |
| Biomarker Full Name | T2-weighted images |
| Biomarker Type | Diagnostic |
| Biomolecule | None |
| Geographical Location | USA |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | 1.4 fold |
| Pathway | None |
| Disease Introduction Mechanism | Cryptococcus neoformans (CN) is an encapsulated yeast that has been classified into three capsular serotypes. The serotype A isolates are referred to as CNvar grubii and account for 95% of cryptococcal infections worldwide. The micro- organism is ubiquitous and can be acquired by inhalation to cause a pulmonary infection. |
| Technique | Analytic |
| Analysis Method | MRI (magnetic resonance imaging) |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | MRI (magnetic resonance imaging) |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
