| DB ID | MyCo_5220 |
| Title | Metabolic Biomarker Panels of Response to Fusarium Head Blight Infection in Different Wheat Varieties |
| Year | 2016 |
| PMID | 27101152 |
| Fungal Diseases involved | Fusarium Head Blight infection |
| Associated Medical Condition | None |
| Genus | Fusarium |
| Species | graminearum |
| Organism | Fusarium graminearum |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Plant extracts |
| Sample source | Plant extracts |
| Host Group | Plant |
| Host Common name | Wheat |
| Host Scientific name | Triticum aestivum |
| Biomarker Name | Inositols |
| Biomarker Full Name | Inositols |
| Biomarker Type | Diagnostic |
| Biomolecule | Metabolite |
| Geographical Location | Canada |
| Cohort | All experiments were conducted in the environment-controlled growth chamber. Canadian germplasm‘FL62R1’ was developed by Dr. André Comeau and Francois Langevin (AAFC- St. Foy). Canadian germplasm‘Stettler’ and‘Muchmore’ were developed by Drs. Ron DePauw and Richard Cuthbert (AAFC-Swift Current). Wheat seeds were sown in peat pots (diameter, 12.7 cm) and maintained in a growth chamber at 21°C/19°C:day/night cycle, with 16 h of light per day until flowering. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Fusarium head blight (FHB) is a fungal disease affecting different crops including major agricultural crops. FHB is mostly caused by fungal pathogen Fusarium graminearum Schwabe. FHB is becoming a major wheat disease in North America causing major losses in productivity. Even more importantly, the infected crop may contain significant levels of various mycotoxins which are highly hazardous to human and animal consumers. FHB is currently treated with highly environmentally hazardous chemical fungicides that are effective only when used under specific conditions. More resistant varieties and agricultural practices can help, however as none of the currently available varieties are fully resistant, these measures have been proven inadequate in severe epidemics. Thus novel, more resistant wheat varieties as well as innovative, non-toxic fungicides are sorely needed. While striving towards those ultimate goals it is also important to develop methods for quick and inexpensive detection of reduced susceptibility in wheat as well as early detection of infection in crop allowing targeted treatment planning. |
| Technique | Analytic |
| Analysis Method | Metabolomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | NMR |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
