| DB ID | MyCo_5030 |
| Title | Preliminary evidence for a serum disaccharide signature of invasive Candida albicans infection detected by MALDI Mass Spectrometry |
| Year | 2015 |
| PMID | 25636941 |
| Fungal Diseases involved | Invasive candidiasis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | All the sera used in this study were sampled from patients followed in Lille University Hospital. No additional sampling was necessary. As sera were taken from a registered biological collection, according to French law, patients consent was not required. An institutional review board approval was given by the‘Comité de Protection des Personnes Nord-Ouest IV’. Six-week-old to 8-week-old female C57BL/6 mice were main- tained by Charles River Laboratories (L’Arbresle, France). Ex- periments were approved by the Subcommittee on Research Animal Care of the Regional Hospital Centre of Lille, France, and in accordance with the European guidelines (86/609/CEE). |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | disaccharide (peak m/z of at 365) |
| Biomarker Full Name | disaccharide (peak m/z of at 365) |
| Biomarker Type | Diagnostic |
| Biomolecule | Metabolite |
| Geographical Location | France |
| Cohort | Six-week-old to 8-week-old female C57BL/6 mice were main- tained by Charles River Laboratories (L’Arbresle, France). Ex- periments were approved by the Subcommittee on Research Animal Care of the Regional Hospital Centre of Lille, France, and in accordance with the European guidelines (86/609/CEE). |
| Cohort No. | 60 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | MALDI Mass Spectrometry |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | MALDI Mass Spectrometry |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
