MycoBiomDB – Record Details (MyCo_5024)

Biomarker Record Details

Database ID: MyCo_5024
DB IDMyCo_5024
TitleProcalcitonin (PCT) in cardiac surgery: diagnostic value in systemic inflammatory response syndrome (SIRS), sepsis and after heart transplantation (HTX)
Year2000
PMID11068216
Fungal Diseases involvedFungal infection
Associated Medical ConditionNone
GenusNone
SpeciesNone
OrganismNone
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePCT
Biomarker Full NameProcalcitonin
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortSixty patients undergoing coronary artery bypass grafting (CABG) and 14 patients after heart transplantation were included in this prospective study. In the CABG group we had 30 patients without any postoperative complications (group A). Furthermore we took samples of 30 patients who suffered postoperatively from a sepsis (group B, n 15) or a systemic inflammatory response syndrome (C, n 15). In addition we measured the PCT- levels in 65 blood samples of 14 patients after heart transplantation (Group I: rejection > IIa, II: viral infection (CMV), III: bacterial/fungal infection, IV: controls).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodLUMItest Immunoassay
ELISA kitsBrahms Diagnostica, Berlin, Germany, complete diagnostic kit (LUMItest Pro- Calcitonin), (Behring Diagnostica,Marburg, Germany)
Assay DataNone
Validation Techniques usedLUMItest Immunoassay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone