| DB ID | MyCo_4862 |
| Title | Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome |
| Year | 2019 |
| PMID | 30010905 |
| Fungal Diseases involved | Cryptococcal meningitis |
| Associated Medical Condition | HIV-AIDS |
| Genus | Cryptococcus |
| Species | spp. |
| Organism | Cryptococcus spp. |
| Ethical Statement | Written informed consent was given by the patients or their families and ethics approval to the parent study was granted by the Biomedical Research Ethics Committee of the University of KwaZulu-Natal (BF053/09), Monash University (20161197839), and University of Western Australia (RA/4/1/2541). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Plasma |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Plasma IgM |
| Biomarker Full Name | Plasma IgM |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Here included 90 ART-naive, HIV-infected patients with a first episode of CM, of whom 27 developed possible or probable C-IRIS after ART initiation (C-IRIS group) and 63 who did not (no–C-IRIS group). |
| Cohort No. | 90 |
| Age Group | None |
| P Value | p=.0003 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Luminex Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Luminex Assay, ELISA |
| Up Regulation Down Regulation | Decrease |
| Sequence Data | None |
| External Link | None |
