MycoBiomDB – Record Details (MyCo_4789)

Biomarker Record Details

Database ID: MyCo_4789
DB IDMyCo_4789
TitleThe effect of vaginal candidiasis on the levels of the oxidative biomarkers in plasma and tissue samples of diabetic rats
Year2007
PMID17899441
Fungal Diseases involvedVulvovaginal candidiasis
Associated Medical ConditionDiabetes
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementThe animal experiments were conducted according to the ‘Guide for the Care and Use of Laboratory Animals’ of the Ethical Committee of Gazi Univer-sity School of Medicine.
Site of InfectionVagina
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourcePlasma
Host GroupAnimal
Host Common nameRat
Host Scientific nameRattus norvegicus
Biomarker NameRSH
Biomarker Full NameSulphydrile groups or glutathione
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationTurkey
CohortSeventy-five female Wistar albino rats, weighting initially (200 ± .15 g) and 4 weeks of age, were obtained from Gazi University School of Medicine Experimental Animal Research Center. They were housed 4–5 per cage in a room with a 12/12-h light/ dark cycle and ambient temperature of 20–25°C. The rats had free access to food and water.
Cohort No.75
Age GroupNone
P Valuep<0.05
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodLipid peroxidation assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedLipid peroxidation assay
Up Regulation Down RegulationDecrease
Sequence DataNone
External LinkNone