| DB ID | MyCo_4733 |
| Title | Candida parapsilosis Cell Wall Proteome Characterization and Effectiveness against Hematogenously Disseminated Candidiasis in a Murine Model |
| Year | 2023 |
| PMID | 36992262 |
| Fungal Diseases involved | Candidemia |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | parapsilosis |
| Organism | Candida parapsilosis |
| Ethical Statement | All animal studies were performed according to the protocol for the care and use of animals sanctioned by the Animal Research Ethics Committee (AREC), University of the Witwatersrand, Johannesburg, South Africa (AREC- 2022/01/01/C). The protocol was inspected and approved by the Institutional Biosafety Committee (IBC) and the Department of Agriculture, Land Reform and Rural Development (DALRRD). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | Candida ALS N domain-containing protein |
| Biomarker Full Name | Candida ALS N domain-containing protein |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | South Africa |
| Cohort | BALB/c mice, 8 to 10 weeks old, were used for this study. The mice were acclimatized for a week and weighted weekly (18–21 g). A total of 36 BALB/c mice were used in the animal model. |
| Cohort No. | 36 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Bioinformatics analysis |
| Analysis Method | LC–MS based Bioinformatic and Functional Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | LC–MS based Bioinformatic and Functional Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | CPAR2_404800 |
| External Link | None |
