MycoBiomDB – Record Details (MyCo_4724)

Biomarker Record Details

Database ID: MyCo_4724
DB IDMyCo_4724
TitleProteomic profiling of aspergillus flavus endophthalmitis derived extracellular vesicles in an in-vivo murine model
Year2022
PMID36002004
Fungal Diseases involvedAspergillus endophthalmitis
Associated Medical ConditionNone
GenusAspergillus
Speciesflavus
OrganismAspergillus flavus
Ethical StatementAll procedures were approved by the Institutional Animal Ethics Committee (IAEC)-SLL/PCT/IAEC/20-21/A.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceEVs protein samples
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameAPIMI
Biomarker Full NameVitamin D-binding protein Gc 2.0120 Q61233 —Plastin-2 LcP1 1.96a P35585 AP-1 complex subunit mu-1
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationIndia
CohortSix-eight weeks old C57BL/6 mice were acquired and housed at the Sipra Labs (Hyderabad, India) . Mice were maintained in 12h (h) light/dark cycle, and fed commercial pelleted diet and water adlibitumatanambient temperature20–26°Cand30– 50% relative humidity.
Cohort No.None
Age GroupNone
P Valuep= 1.85
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueLiquid chromatography
Analysis MethodLC-MS/MS based Proteomics Approach
ELISA kitsNone
Assay DataNone
Validation Techniques usedLC-MS/MS based Proteomics Approach
Up Regulation Down RegulationDown regulated
Sequence DataUniprot ID: 21614
External LinkNone