| DB ID | MyCo_4681 |
| Title | Proteomic profiling of aspergillus flavus endophthalmitis derived extracellular vesicles in an in-vivo murine model |
| Year | 2022 |
| PMID | 36002004 |
| Fungal Diseases involved | Aspergillus endophthalmitis |
| Disease | Aspergillosis (Aspergillus Infection) |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | flavus |
| Organism | Aspergillus flavus |
| Ethical Statement | All procedures were approved by the Institutional Animal Ethics Committee (IAEC)-SLL/PCT/IAEC/20-21/A. |
| Site of Infection | Unspecified |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | EVs protein samples |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | ATP6VIEL |
| Biomarker Full Name | V-type proton ATPase subunit E 1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | India |
| Cohort | Six-eight weeks old C57BL/6 mice were acquired and housed at the Sipra Labs (Hyderabad, India) . Mice were maintained in 12h (h) light/dark cycle, and fed commercial pelleted diet and water adlibitumatanambient temperature20–26°Cand30– 50% relative humidity. |
| Cohort No. | None |
| Age Group | None |
| P Value | p= 1.82 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Sub Technique | LC-MS + Computational |
| Technique | Hybrid Methods |
| Analysis Method | LC-MS/MS based Proteomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | LC-MS/MS based Proteomics Approach |
| Up Regulation Down Regulation | Down regulated |
| Sequence Data | Uniprot ID: PS0518 |
