| DB ID | MyCo_4440 |
| Title | Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study |
| Year | 2023 |
| PMID | 37679727 |
| Fungal Diseases involved | Cryptococcal meningitis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | spp. |
| Organism | Cryptococcus spp. |
| Ethical Statement | The study protocol was approved by the Institutional Review Board of the First Affiliated Hospital of Fujian Medical University (No, MRCTA, ECFAH of FMU, [2020]265). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Cerebrospinal fluid (CSF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | NGAL |
| Biomarker Full Name | Neutrophil Gelatinase Associated Lipocalin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | In the current study, here prospectively enrolled patients with suspected CNS infections, in the First Affiliated Hospital of Fujian Medical University (Fuzhou, China) from May 2019 to June 2022. In the current study, here prospectively obtained 231 patients with suspected CNS infections at admission, BM (n=67), TBM (n=55), CM (n=51), and an age- and sex-matched hospitalized control (HC,n=58). |
| Cohort No. | 51 |
| Age Group | 14–73 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Assay |
| Analysis Method | Latex enhanced immunoturbidimetry Analysis |
| ELISA kits | None |
| Assay Data | FDA Approved commercialized kit (the Latex enhanced immunoturbidimetry methods), from Wuhan Life Origin Biotech Joint Stock Co., Ltd. |
| Validation Techniques used | Latex enhanced immunoturbidimetry Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
