MycoBiomDB – Record Details (MyCo_4430)

Biomarker Record Details

Database ID: MyCo_4430
DB IDMyCo_4430
TitleRisk Factors for the Mortality of Pneumocystis jirovecii Pneumonia in Non-HIV Patients Who Required Mechanical Ventilation: A Retrospective Case Series Study
Year2017
PMID28567422
Fungal Diseases involvedPneumocystis jirovecii pneumonia
Associated Medical ConditionNone
GenusPneumocystis
Speciesjirovecii
OrganismPneumocystis jirovecii
Ethical StatementThes tudy protocol was approved by ethics committee of our hospital (No.2721)., TokyoWomen’sMedicalUniversity,Tokyo162-8666,Japan.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameKL-6
Biomarker Full NameKL-6
Biomarker TypePrognostic
BiomoleculeProtein
Geographical LocationJapan
CohortA retrospective chart review was performed of all patients admitted to our multidisciplinary general inten-sive care unit (ICU) from December 2008 until January 2012 who were diagnosed with PCP and treated for acute hypoxemicrespiratory failure with any types of MV. During the study period, we sus- pected that 28 patients had PCP, based on their symptoms, radiographs, and history of underlying disease. Of these, 21 patients were diagnosed with PCP,and20(95%)required MV.
Cohort No.28
Age Group37-86
P Valuep=0.608
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodKL-6 assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedKL-6 assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone