| DB ID | MyCo_4420 |
| Title | Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy |
| Year | 2020 |
| PMID | 32170382 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Extracted Conidia |
| Sample source | Extracted conidia |
| Host Group | None |
| Host Common name | None |
| Host Scientific name | None |
| Biomarker Name | TAFC |
| Biomarker Full Name | Triacetylfusarinine C |
| Biomarker Type | Diagnostic |
| Biomolecule | Siderophore |
| Geographical Location | Germany |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive aspergillosis (IA) is one of the most common invasive fungal infections, mainly affecting immunocompromised patients and predominantly caused by the mold Aspergillus fumigatus. This severe infection is associated with 90- day mortality rates of more than 60% depending on the patient cohort. One reason for these high mortality rates is the challenging diagnosis of Aspergillus infections. |
| Technique | Analytic |
| Analysis Method | Interference-enhanced Raman spectroscopy |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Interference-enhanced Raman spectroscopy |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
