MycoBiomDB – Record Details (MyCo_4364)

Biomarker Record Details

Database ID: MyCo_4364
DB IDMyCo_4364
TitleImmunoproteomics based identification of thioredoxin reductase GliT and novel Aspergillus fumigatus antigens for serologic diagnosis of invasive aspergillosis
Year2012
PMID22251604
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementThe study protocol was approved by the Ethics Committee of the hospital and informed consent was obtained from all patients included in the study
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameMalate dehydrogenase, NAD-dependent
Biomarker Full NameMalate dehydrogenase, NAD-dependent
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortSix patients with proven IA, and different underlying dis- eases and expressing high levels of anti-Aspergillus antibo-dies were selected for the immunoproteomic analysis.
Cohort No.6
Age Group30-65
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueBioinformatics analysis
Analysis MethodImmunoproteomics Approach
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunoproteomics Approach
Up Regulation Down RegulationPositive
Sequence DataGenBank Accession No: GI:70986899
External LinkNone