MycoBiomDB – Record Details (MyCo_4176)

Biomarker Record Details

Database ID: MyCo_4176
DB IDMyCo_4176
TitleEvaluation of procalcitonin, neopterin, C-reactive protein, IL-6 and IL-8 as a diagnostic marker of infection in patients with febrile neutropenia
Year2008
PMID18661397
Fungal Diseases involvedFungal infection
Associated Medical ConditionFebrile neutropenia
GenusNone
SpeciesNone
OrganismNone
Ethical StatementThe study was approved by the institutional ethics committee, and informed consent was signed by all the patients included.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePCT
Biomarker Full NameProcalcitonin
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortPatients with an underlying hematologic malignancy at the time of diagnosis and who received antineo-plastic chemotherapy and had developed neutropenia (neutrophils 5 500/mm3) and fever (temperature 388C) were included in the study. A total of 57 febrile neutropenic fever episodes from 56 patients were studied to measure PCT, CRP, neopterin, IL-6 and IL-8 at diagnosis of fever of infectious origin.
Cohort No.56
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodImmunoluminometric assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunoluminometric assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone