| DB ID | MyCo_4156 |
| Title | Pneumocystis carinii pneumonia in South African children infected with human immunodeficiency virus |
| Year | 2000 |
| PMID | 10917216 |
| Fungal Diseases involved | Pneumocystis carinii pneumonia |
| Associated Medical Condition | HIV-AIDS |
| Genus | Pneumocystis |
| Species | carinii |
| Organism | Pneumocystis carinii |
| Ethical Statement | The study was approved by the Research and Ethics Committee of the University of Cape Town. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | LDH |
| Biomarker Full Name | Lactate dehydrogenase |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | South Africa |
| Cohort | 151 HIV-infected children were included in the study. |
| Cohort No. | 151 |
| Age Group | Mar-23 |
| P Value | p<0.001 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Pneumocystis carinii pneumonia (PCP) has been regarded as uncommon in HIV-infected patients in Africa in contrast to the high incidence reported in developed countries in the early stages of the HIV epidemic. Although tuberculous, pyogenic and inter- stitial pneumonia have been reported to predominate among HIV-infected African adults, PCP has been increasingly found. Differences in patient selection criteria, difficulties in diagnosing PCP or true geo- graphic variation in the prevalence or virulence of P. carinii might account for such results. |
| Technique | Immunological assay |
| Analysis Method | Immunological Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunological Assay |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
