| DB ID | MyCo_4138 |
| Title | A comprehensive pathophysiology of dandruff and seborrheic dermatitis - towards a more precise definition of scalp health |
| Year | 2013 |
| PMID | 22875203 |
| Fungal Diseases involved | Dandruff and Seborrheic Dermatitis |
| Associated Medical Condition | None |
| Genus | Malassezia |
| Species | spp. |
| Organism | Malassezia spp. |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-8 |
| Biomarker Full Name | Interleukin-8 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | p<0.0001 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Dandruff and seborrheic dermatitis (D/SD) are common afflictions of the human scalp and considered the same basic condition differing only in magnitude. Heredity plays only a small role in developing a predisposition for the condition. A comprehensive review of the pathop- hysiological changes in the stratum comeum (SC) in these conditions at the macro (signs and symptoms), micro (phy- siological structure and function) and biomolecular strata may enable a precise and more complete determination of the condition of the scalp and also the therapeutic responses to treatment leading to restoration of homeostasis. Amore complete description of the pathophysiology of the D/SD condition results from combining these 3 informational strata. This combination can lead to a paradigm shift in describing what constitutes a return to "scalp health." |
| Technique | Immunological assay |
| Analysis Method | Immunological Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunological Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
