| DB ID | MyCo_4128 |
| Title | Predictive factors for disseminated histoplasmosis in AIDS patients with fever admitted to a reference hospital in Brazil |
| Year | 2017 |
| PMID | 30133631 |
| Fungal Diseases involved | Histoplasmosis |
| Associated Medical Condition | HIV-AIDS |
| Genus | Histoplasma |
| Species | capsulatum |
| Organism | Histoplasma capsulatum |
| Ethical Statement | This study was approved by the Ethical Review Board of São José Hospital of Infectious Diseases, Fortaleza, Brazil. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | LDH (≥5x) |
| Biomarker Full Name | Lactate dehydrogenase (≥5x) |
| Biomarker Type | Predictive |
| Biomolecule | Protein |
| Geographical Location | Brazil |
| Cohort | A total of 165 AIDS patients with a presumptive diagnosis of DH were identified. Forty-eight patients were excluded because a fungal culture was not performed (n = 29), empirical treatment with amphotericin B elicited a response despite a negative fungal culture (n = 15), or no diagnosis was established at discharge (n = 4); the remaining 117 (70.9%) subjects were included in the data analysis. |
| Cohort No. | 117 |
| Age Group | 18-62 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Immunological Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunological Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
