MycoBiomDB – Record Details (MyCo_4096)

Biomarker Record Details

Database ID: MyCo_4096
DB IDMyCo_4096
TitleMonocyte human leukocyte antigen-DR but not β-D-glucan may help early diagnosing invasive Candida infection in critically ill patients
Year2021
PMID34417900
Fungal Diseases involvedInvasive candidiasis
Associated Medical ConditionCritically ill patients
GenusCandida
Speciestropicalis
OrganismCandida tropicalis
Ethical StatementThe study was approved by the ethic committee (Comité de Protection des Personnes Sud-Mediterranée III, 2014-A00500-47) and followed the STARD guidelines
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamemHLA-DR < 5000 Ab/c
Biomarker Full NameMonocyte human leukocyte antigen-DR < 5000 Ab/c
Biomarker TypeDiagnostic
BiomoleculeAntigen
Geographical LocationFrance
CohortFifty patients were included in the study.
Cohort No.50
Age Group60.5–71.3
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodImmunological assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedImmunological assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone