| DB ID | MyCo_4060 |
| Title | Diagnostic accuracy of eosinophil-to-lymphocyte ratio and eosinophil-to-neutrophil ratio as biomarkers for differentiating between fungal and bacterial infection in necrotising otitis externa |
| Year | 2024 |
| PMID | 38263617 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | Necrotizing otitis externa |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | The research complied with and approved by the medical cen-tre's institutional review board, the Human Subjects Research Committee. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | ELR |
| Biomarker Full Name | Eosinophils‐to‐Leukocyte Ratio |
| Biomarker Type | Prognostic |
| Biomolecule | None |
| Geographical Location | Israel |
| Cohort | A retrospective study of NOE patients was conducted following STARD criteria. Out of 75 patients with NOE, 50 had a positive swab culture from hospitalisation. Of them, 30 demonstrated bacterial growth (26 PSA, 2 Staphylococcus aureus (SA) and 2 Proteus) and 17 demonstrated fun- gal growth (12 Candida, 4 Aspergillus and 1 Mucor). |
| Cohort No. | 75 |
| Age Group | 72.6 ± 10.9 |
| P Value | p=0.009 |
| Sensitivity | 0.88 |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Immunological assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunological assay |
| Up Regulation Down Regulation | Decrease |
| Sequence Data | None |
| External Link | None |
