MycoBiomDB – Record Details (MyCo_4059)

Biomarker Record Details

Database ID: MyCo_4059
DB IDMyCo_4059
TitleElevated serum CA19-9 level and regional lymphadenopathy in a young man with allergic bronchopulmonary aspergillosis
Year1998
PMID9510409
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameCA19-9
Biomarker Full NameCA19-9
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortA 2 1 -year-old nonsmoking man with bronchial asthma was admitted to the hospital because of productive cough with pulmonary infiltrates, was included in the study.
Cohort No.1
Age Group21
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismAlergic bronchopulmonary aspergillosis (ABPA) is a hy- persensitivity reaction to the fungus Aspergillus that was first described by Hinson et al in 1952. It has been recognized more frequently in recent years with the diagnosis based on a combination of clinical, immunologic and radiologic criteria. The generally recognized features of ABPA include bron- chial obstruction (asthma), peripheral blood eosinophilia, el- evated serum immunoglobulin E (IgE) concentration, immedi- ate skin reactivity to Aspergillus antigen, precipitating antibod- ies against Aspergillus antigen, transient or fixed pulmonary infiltrates and central bronchiectasis.
TechniqueImmunological assay
Analysis MethodImmunological Assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunological Assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone