| DB ID | MyCo_4058 |
| Title | Disseminated aspergillosis in an immunocompetent patient with detectable bis(methylthio)gliotoxin and negative galactomannan |
| Year | 2016 |
| PMID | 27939578 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | Immunocompetent patient |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | bmGT |
| Biomarker Full Name | Bis(methylthio)gliotoxin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Spain |
| Cohort | A 70-year-old male, with non-insulin dependent type II diabetes mellitus and a past surgery history of aortic valve replacement with coronary by-pass five years ago, was seen in the emergency department with blurred vision was included in the study. |
| Cohort No. | 1 |
| Age Group | 70 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive aspergillosis (IA) is the most frequent filamentous fun-gal disease in immunocompromised patients. Immunosuppressed hosts get infected by conidial inhalation, and pulmonary aspergillosis is the most frequent clinical presentation. Dissemination occurs from the lungs by hyphal invasion. |
| Technique | Immunological assay |
| Analysis Method | Immunological Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunological Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |