MycoBiomDB – Record Details (MyCo_4058)

Biomarker Record Details

Database ID: MyCo_4058
DB IDMyCo_4058
TitleDisseminated aspergillosis in an immunocompetent patient with detectable bis(methylthio)gliotoxin and negative galactomannan
Year2016
PMID27939578
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionImmunocompetent patient
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamebmGT
Biomarker Full NameBis(methylthio)gliotoxin
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortA 70-year-old male, with non-insulin dependent type II diabetes mellitus and a past surgery history of aortic valve replacement with coronary by-pass five years ago, was seen in the emergency department with blurred vision was included in the study.
Cohort No.1
Age Group70
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismInvasive aspergillosis (IA) is the most frequent filamentous fun-gal disease in immunocompromised patients. Immunosuppressed hosts get infected by conidial inhalation, and pulmonary aspergillosis is the most frequent clinical presentation. Dissemination occurs from the lungs by hyphal invasion.
TechniqueImmunological assay
Analysis MethodImmunological Assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunological Assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone