MycoBiomDB – Record Details (MyCo_3988)

Biomarker Record Details

Database ID: MyCo_3988
DB IDMyCo_3988
TitleThe use of MUC5B antibody in identifying the fungal type of fungal sinusitis
Year2008
PMID18439938
Fungal Diseases involvedFungal sinusitis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveOpportunistic
Sample typeNone
Sample sourceNone
Host GroupNone
Host Common nameNone
Host Scientific nameNone
Biomarker NameMUC5B
Biomarker Full NameMUC5B
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortNone
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismCandida albicans, Aspergillus spp, and Mucorales are the most common pathogenic fungi and often the cause of fungal sinusitis. The prognosis and therapeutic options for these various opportunistic fungal infections are different; early identification is critical. Proper diagnosis and treatment can prevent the infection progressing from noninvasive state to invasive state. Morphological measures such as arrangement and shape do not suffice as a diagnostic particularly when only a small quantity of swollen and anamorphic fungi is available. Thus, there is an important need for sensitive diagnostic assays.
TechniqueImmunological assay
Analysis MethodImmunohistochemistry Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunohistochemistry Analysis
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone