| DB ID | MyCo_3982 |
| Title | The use of MUC5B antibody in identifying the fungal type of fungal sinusitis |
| Year | 2008 |
| PMID | 18439938 |
| Fungal Diseases involved | Fungal sinusitis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | niger |
| Organism | Aspergillus niger |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | None |
| Sample source | None |
| Host Group | None |
| Host Common name | None |
| Host Scientific name | None |
| Biomarker Name | MUC5B |
| Biomarker Full Name | MUC5B |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Candida albicans, Aspergillus spp, and Mucorales are the most common pathogenic fungi and often the cause of fungal sinusitis. The prognosis and therapeutic options for these various opportunistic fungal infections are different; early identification is critical. Proper diagnosis and treatment can prevent the infection progressing from noninvasive state to invasive state. Morphological measures such as arrangement and shape do not suffice as a diagnostic particularly when only a small quantity of swollen and anamorphic fungi is available. Thus, there is an important need for sensitive diagnostic assays. |
| Technique | Immunological assay |
| Analysis Method | Immunohistochemistry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immunohistochemistry Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
