| DB ID | MyCo_3947 |
| Title | Candida biomarkers in patients with candidaemia and bacteraemia |
| Year | 2015 |
| PMID | 25900160 |
| Fungal Diseases involved | Candidemia |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | parapsilosis |
| Organism | Candida parapsilosis |
| Ethical Statement | The study was approved by the local ethics committee (CEIC-A1, ref. 350/12) and the relevant Spanish authorities [Agencia Espan ˜ ola del Medicamento y Productos Sanitarios, AEMPS (Spanish Agency for Medicines and Health Care Products)]. The use of stored sera was authorized with a waiver of informed consent by the ethics committee. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CAGTA |
| Biomarker Full Name | Candida albicans germ tube antibody (CAGTA) |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Spain |
| Cohort | Here studied serum samples from adult patients with candidaemia (n= 31) |
| Cohort No. | 31 |
| Age Group | None |
| P Value | None |
| Sensitivity | 58.1 |
| Specificity | 92 |
| Positive Predictive Value | 81.8 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Immunofluorescence test |
| ELISA kits | CAGTA Immunofluorescence test Kit (Vircell Microbiologist S.L., Granada, Spain), Platelia Candida Ag Plus assay kit (Bio-Rad, Marnes-la-Coquette, France). |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | FDA Approved-Fungitell assay, Immunofluorescence test, Platelia Candida Ag Plus assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
