MycoBiomDB – Record Details (MyCo_3944)

Biomarker Record Details

Database ID: MyCo_3944
DB IDMyCo_3944
Titleβ-D-Glucan and Candida albicans germ tube antibody in ICU patients with invasive candidiasis
Year2015
PMID26134359
Fungal Diseases involvedInvasive candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementThe study protocol was approved by the institutional review board, Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, Spain and informed consent was obtained from the patients or their legal representatives.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameCAGTA
Biomarker Full NameCandida albicans germ tube antibody (CAGTA)
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortBetween 1 January 2011 and 30 December 2012, unse-lected, non-neutropenic critically ill patients admitted for at least 7 days to a medical-surgical ICU in Sevilla, Spain, were included in a prospective, cohort, and observational study. Of 148 eligible patients, 41 (27.7 %) were excluded.
Cohort No.107
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodImmunofluorescence test
ELISA kitsImmunofluorescence test Kit (VircellÒ kit assay, Granada, Spain)
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedImmunofluorescence test
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone