| DB ID | MyCo_3900 |
| Title | Interferon gamma as an immune modulating adjunct therapy for invasive mucormycosis after severe burn - A case report |
| Year | 2022 |
| PMID | 36072605 |
| Fungal Diseases involved | Mucormycosis |
| Associated Medical Condition | None |
| Genus | Rhizopus |
| Species | microsporus |
| Organism | Rhizopus microsporus |
| Ethical Statement | Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. The patients/participants provided their written informed consent to participate in this study. Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article. |
| Site of Infection | None |
| Opportunistic invasive | Invasive/Opportunistic |
| Sample type | Biopsy |
| Sample source | Extracted tissue |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IFN-γ |
| Biomarker Full Name | Interferon gamma |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | France |
| Cohort | Here report the case of a 61-year-old woman, with a medical history of hypertension, active smoking and bipolar disease, no history of diabetes, who suffered third-degree burns on 43% of her total body surface area (neck, thorax, back and the four limbs) after an accidental fire. |
| Cohort No. | 1 |
| Age Group | 61 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Mucormycosis infection is a rare, rapidly progressing and often fatal disease caused by the Mucorales fungi. This type of infection is opportunistic and affects m a i n l y immunocompromised patients suffering from severe underlying conditions such as hematological disorders, organ transplantation or longstanding diabetes. |
| Technique | Immunological assay |
| Analysis Method | Immune monitoring with IFN-γ |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Immune monitoring with IFN-γ |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
