| DB ID | MyCo_3890 |
| Title | Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans |
| Year | 2008 |
| PMID | 18249133 |
| Fungal Diseases involved | Candida sepsis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Body fluid |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | TNF-α |
| Biomarker Full Name | Tumor Necrosis Factor alpha |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Germany |
| Cohort | In this study, 325 posttraumatic patients with sepsis and septic shock were collected over a period of 4 years. Over a ten-month period, 47 of these 325 patients were monitored daily during their treatment in the anesthesiological intensive care unit (ICU) of the University Hospital Ulm, Germany. |
| Cohort No. | 47 |
| Age Group | 57.3 ± 10.4 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Assay |
| Analysis Method | Human cytokine Lincoplex assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Pyrosequencing Analysis, Human cytokine Lincoplex assay |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |